Home Remedies for Anorexia
Discussion Bulimia nervosa is characterized by binge eating followed by purging, which is accomplished by self-induced vomiting, laxative use, or use of diuretics. The prevalence of this condition in the United States is approximately 1.5 among young women but is rarely seen in men. The typical patient is usually somewhat underweight and binges and purges several times a week. Dietary intake may be very restricted, with nonpurged caloric intake averaging 1,000 kcal day. Depression is often comorbid.
Eating disorders are associated most commonly with younger women -teenagers and young adults. Anorexia nervosa rarely persists into later life, but without successful treatment it may be fatal. When anorexia does last into mid life, serious health consequences can arise due to prolonged malnutrition. These include heart failure, liver damage, and hypokalemia-induced arrhythmias. In contrast, bulimia and binge eating can persist for years and may be associated with obesity. Purging is less common in mature women than in adolescents and may take different forms. Self-induced vomiting is unlikely to be continued into mid life and would likely result in severe dental damage if it were. Laxative and diuretic abuse may be more likely in this age group. Underweight patients are easy to identify and question further about eating habits. Because many bulimics are normal weight or heavier, they are more difficult to recognize. Routine questions maybe helpful in identifying patients for more...
Blocked by a non-specific melanocortin receptor antagonist (93-98). Furthermore, phosphatidylinositol-3-OH kinase (PI(3)K), an intracellular mediator of insulin signaling (99), appears to play a crucial role in the leptin-induced anorexia signal transduction pathway as well (99). Leptin functionally enhances or sensitizes some actions of insulin. The underlying molecular mechanisms for the insulin-sensitizing effects of leptin are unclear, and studies are conflicting regarding the effect of leptin on insulin-stimulated signal transduction. Whereas the long form of the leptin receptor has the capacity to activate the JAK STAT3 (100,101) and mitogen-activated protein kinase (MAPK) pathways, leptin is also able to stimulate tyrosine phosphorylation of insulin receptor substrate (IRS-1) (101), and to increase transcription of fos, jun (102).
Examples include children's transient terrors of darkness or animals, fears of cancer that wax and wane with a depressive illness, worry about going out as part of paranoid schizophrenia, apprehension of being fat in anorexia nervosa, preoccupation with other aspects of one's appearance or smell in dysmorphophobia (body dysmorphic disorder) and persistent panic in various public places in a housebound agoraphobic. Some regard phobias as maladaptive ''habits'' that themselves constitute the problem without any underlying cause, while others think of them as a surface aspect of deeper pathology. The varying significance of different phobic phenomena is hard to grasp if we posit a unitary origin for all of them instead of recognizing that varied factors may play a role in their genesis.
A Canadian study led by Tannock et al. 17 randomized 161 symptomatic patients with HRPC to receive either mitoxantrone every 3 weeks with daily prednisone or prednisone alone. The primary end point of this study was palliative response, which was defined as a significant improvement in either pain or analgesic usage or both (neither could get worse). In the mitox-antrone arm, a statistically significant improvement in pain relief (29 vs. 12 , p .01) and a prolonged duration of this palliative response (43 weeks vs. 18 weeks, p .0001) was demonstrated. These patients also reported improvements in physical and social functioning, global quality of life, anorexia, drowsiness, constipation, and other symptoms 18 . The use of mitoxantrone was also associated with a higher PSA response rate and time to progression. There was no survival benefit of chemotherapy, although a crossover to mitoxantrone in patients who progressed on prednisone was allowed and may have impacted on the survival...
Such a mechanistically based classificatory system can help the prescriber in four specific ways. First, it can be used to anticipate and understand the pharmacological effects that these drugs will produce in most patients. Second, it can facilitate the selection of a specific agent for a patient with a specific symptom cluster (e.g. insomnia and anorexia versus hypersomnia
At the other extreme, cycle disturbances also occur in association with obesity. Almost 50 years ago, before anorexia nervosa became common, a higher prevalence of obesity was observed among amenorrheic women.32 More-recent literature suggests that anovulatory cycles are more common among obese women,33,34 and that weight loss in these individuals results in improved ovulation and ability to become pregnant.35 Whether levels of cognitive dietary restraint differ between vegetarians and omnivores may depend on the motivation for vegetarianism. Some women with high levels of cognitive dietary restraint may adopt a vegetarian diet as a means of limiting food intake. Supportive evidence is provided by studies of women with anorexia nervosa, a condition characterized by very high levels of restraint. Among consecutive cases in two patient series, 45 and 54 were vegetarian.57,58 And in a survey of 158 In contrast, in a study of carefully selected vegetarians and omnivores (the inclusion...
Diagnosis and Classification of Phobias and Other Anxiety Disorders Quite Different Categories or Just One Dimension
Even considering the categorical classification adopted by both ICD-10 and DSM-IV-TR, Marks and Mataix-Cols offer a classification of phobias that roughly supports the idea of a unique dimension for anxiety disorders and also include some other disorders (such as panic, depression and anorexia nervosa) which are often associated with phobias. In a merge to normality states, Marks and Mataix-Cols propose a new category of phobialike syndromes not called phobias (jointly with obsessive-compulsive disorder, post-traumatic stress disorder, somatoform disorders and avoidant personality disorder) that they call touch and sound aversions.
Eating disorders and schizophrenia were associated with most days ill in bed, disability days, and Short Form-36 (SF-36) role limitations due to emotional problems. On each of these measures the affective disorders ranked third, with the anxiety and substance use disorders fourth and fifth, respectively. The substantial minority of people with comorbid disorders were comparable in disability level to people with schizophrenia or eating disorders. Regression strategies are cumbersome. As mentioned above, Andrews et al. 29 used the principal complaint technique to circumvent the problem posed by comorbidity. They studied the four largest diagnostic groups in their survey affective, anxiety, personality and substance use disorders. Anxiety disorders ranked second, after the affective disorders, as determinants of disability as measured by the mental health summary scale of the SF-12 (mean score 40 affective 33, personality disorder 46 and substance use disorder 49)....
Patients present with a nonspecific viral illness initially. They may complain of anorexia, irritability, and lethargy. Bone marrow failure leads to pallor, bleeding, and fever. The presenting clinical features of leukemia are similar to those of aplastic anemia (anemia, bruising, frequent infection), but they also include lymphadenopathy, splenomegaly, and bone pain. Many of the patients have had signs or symptoms less than 4 weeks.
HPI She suffers from episodes of binge eating and self-induced vomiting (bulimia). syndrome) is usually seen following protracted and forceful vomiting of solid food it is common in alcoholics, bulimics, and pregnant women and in any condition that increases intraabdominal pressure. The esophagus has three anatomic constrictions the cardiac (the most common site of rupture), the aortic arch, and the cricopharyngeal.
Cutaneous leishmaniasis may heal spontaneously, yet the following treatments yield good results trivalent antimonials administered parenterally such as repodral and anthiomalin 2-3 ml (0.02-0.03 g) on alternate days in 12-20 doses and the pentavalents like glucantime (meglumine antimoniate) 10-20 mg kg for 12 days to 3 weeks or until the lesions have healed. Another medication, pentostam (sodium stibogluconate) 20 mg kg day may be given for 20 days. For cutaneous disease antimonials may be injected intralesionally 0.2-15 ml weekly. Local antiseptics should be used. Sulfate of paromomycyn 15 and methylbenzetonio chloride 12 twice a day for 10 days and up to three weeks, or bleomycin 1 intralesionally are recommended. Also thermotherapy (local heat), cryosurgery, curettage, laser and radiotherapy have been used. In cutaneous leishmaniasis diaminodiphenylsulfone (Dapsone), 3 mg kg day for 3 weeks, has yielded good results. In cases caused by L. m.mexicana there is a good response to...
Concurrent studies also took increasing note that kwashiorkor, the most severe form of protein energy malnutrition, was often preceded by an infection such as acute diarrheal disease,19 measles,20 or chicken pox.21 Prospective birth cohort studies revealed that breast-fed children in impoverished settings grew in parallel to children in industrialized settings. However, when weaning foods were introduced and the incidence of both diarrhea and respiratory illness increased, growth faltering occurred. Even asymptomatic gastrointestinal infections led to growth faltering.5 Measured observations of children during infectious disease episodes showed that common infections led to anorexia, nutrient malabsorption, micronutrient wasting, and growth deficits.22-27 Diverse infections often occurred at a rate that continually delayed the ability of a child to achieve adequate catch-up in nutritional status or linear growth, and the child entered a cycle of infections and worsening nutritional...
Female monkeys will initiate ovulatory menstrual cycles.4 Similarly, exogenous GnRH administration to young women with anorexia nervosa and delayed puberty will also induce the onset of pubertal changes and menarche.5 The causes of the increased activity of the GnRH pulse generator at the onset of puberty are not, however, known with cer-tainty.3
ID CC A 64-year-old male with metastatic lung cancer is seen with complaints of severe bone pain, anorexia, and cachexia. Discussion Cachexia anorexia syndrome is characterized by progressive weight loss, lipolysis, loss of muscle mass, anorexia, diarrhea, and fever in patients with end-stage cancer or AIDS. Some drugs that have proven effective in improving appetite and treating cachexia include megestrol acetate and dronabinol. Megestrol is a synthetic progesterone that stimulates the appetite, resulting in weight gain and recovery of muscle mass. It is relatively nontoxic. Side effects are rare and include altered menses with unpredictable bleeding and mild edema. Dronabinol, a synthetic tetrahydrocannabinol (THC), is the active component in marijuana and is used to treat nausea and vomiting associated with cancer chemotherapy as well as to stimulate appetite. Side effects are due mainly to the psychoactive effects of the drug and include dizziness, ataxia, hallucinations...
The motivation for adopting a vegetarian diet may be important, as some women may become vegetarian in the process of developing an eating disorder, with attendant menstrual disturbances. Furthermore, high levels of cognitive dietary restraint are associated with subclinical menstrual disturbances. Accordingly, the subpopulation of women who become vegetarian for reasons related to body weight issues may be at increased risk.
A 40-year-old man without a significant past medical history comes to the emergency room with a 3-day history of fever, shaking chills with a 15-min episode of rigor, nonproductive cough, and anorexia, as well as the development of right-sided pleuritic chest pain and shortness of breath over the last 12 h. A chest roentgenogram reveals a consolidated right middle lobe infiltrate and a CBC shows an elevated neu-trophil count with many band forms present. Which of the following statements regarding pneumonia in this patient is correct
Clostridium perfringens type C has been the cause of both sporadic and epidemic cases of necrotizing enteritis. Clinical entities such as Darmbrand ( bowel gangrene ) in postwar Germany during the 1940s and pigbel97 in the Papua New Guinea highlands have been attributed to this organism, which elicits alpha and beta toxins capable of causing the enteritis. Poor nutrition and episodic dietary indulgence have been associated with these entities, with investigators suggesting that a low level of digestive enzymes in people with low protein dietary intake may prevent normal inactivation of bacterial toxins.98 Clinically, previously healthy patients present with a necrotizing enteritis syndrome that may include anorexia, nausea, vomiting, abdominal pain, and hematochezia and may progress to sepsis. Complications are common and include peritonitis secondary to bowel perforation, ileus, and chronic scarring leading to malabsorption, obstruction, or fistulas.
Appearance concerns gender, it may be called transsexualism or anorexia nervosa. Anorexia nervosa. If the sufferer starves herself because she is convinced she is too fat despite being very underweight in reality, then the problem is called anorexia nervosa, not dysmorphophobia.
Diethylcarbamazine, a piperazine derivative, is well absorbed orally and has a half-life of 8 hours. The parent drug and its metabolites are excreted through the kidney. Side effects include those attributable directly to the drug and those that result from the release of parasite antigens and Wolbachia lipopolysaccharide. Side effects include nausea, vomiting, anorexia, headache, malaise, weakness, arthralgias, and, rarely, acute psychotic reactions. In patients with W bancrofti or B. malayi infection, localized swelling or nodules may develop along lymphatics during treatment, or there may be transient lymphedema or hydrocele formation. Diethylcarbamazine is no longer used in patients with onchocerciasis because it can elicit the Mazzotti reaction, which is characterized by hypotension, pruritus, fever, tachycardia, wheezing, chorioretinitis, and uveitis secondary to the release of microfilarial antigens and Wolbachia lipopolysaccharide. Life-threatening encephalopathy has been...
Overproduction or increased levels of growth hormone can lead to gigantism in children or acromegaly in adults. Gigantism, characterized by abnormally large body proportions and abnormal sexual development, is usually attributed to hypersecretion of growth hormone during childhood. Acromegaly, characterized by enlargement, thickening, and elongation of facial and extremity bones, is the result of hypersecretion of growth hormone in adults. Increased growth hormone levels are also associated with hypoglycemia and anorexia nervosa.
In addition to calorie intake and meal composition, ghrelin levels appear to be influenced by the nutritional status of the individual. The basal level is shown to be reduced in chronic obesity with an attenuated postprandial response (118-120). The latter may explain persistent eating habits in obese patients. Paradoxically, the level is increased during fasting, cachexia (121), in states of malnutrition, and in patients with anorexia nervosa (122). Interestingly, and contrary to these findings, ghrelin levels are reduced after a Roux-en-Y gastric bypass, but not other forms of antiobesity surgery, despite massive weight loss (33). One explanation might be that the surgery involves the removal of the ghrelin-secreting part of the stomach (33,123), although the real mechanism is still unknown. However, in addition to the mechanical restriction owing to reduced stomach size and hence reduced meal portions, it has been hypothesized that the decreased ghrelin level in these patients...
In addition to the studies of GH described earlier in this chapter, transgenic and targeted gene-disruption technologies are used to elucidate the mechanisms controlling food intake, body composition, and the pathogenesis of obesity. Within the past few years, the applications of these genetic techniques in whole animals have identified a number of new molecules and physiologic pathways involved in the regulation of body wt, and have led to important new insights into the pathophysiology of eating disorders and obesity. These include the hormone leptin, the short and long forms of the leptin receptor, uncoupling proteins, agouti and agouti-related proteins, melanocortin-recep-tor isoforms, melanin-concentrating hormone, orexin, mahogany, and the proteins responsible for tub and fat, two monogenic mouse models of obesity. These efforts, in addition to characterization of several spontaneous obese mutants, provided a number of novel genetic models in which a single gene or pathway has...
The role of endotoxin in the pathogenesis of typhoid fever is unclear.69 Investigators at the University of Maryland showed that when S. Typhi endotoxin was initially injected into human volunteers, it produced chills, fever, headaches, myalgias, anorexia, nausea, thrombocytopenia, and leukopenia, as in typhoid fever.66 After these volunteers had received repeated injections of endo-toxin, they became unresponsive (tolerant) to it, but when the tolerant subjects were challenged with S. Typhi, they developed classic typhoid fever. Since typhoid fever is an unrelenting, sustained illness when not treated with antibiotics, the fact that the volunteers developed tolerance to endotoxin suggests that circulating endotoxin does not cause the symptoms and signs of naturally acquired typhoid fever. Furthermore, the facts that endotoxin-tolerant volunteers developed typhoid fever after rechallenge, and that circulating endotoxin as detected by limu-lus assay is not present in many patients with...
Discussion There are two major types of eating disorders anorexia nervosa and bulimia. The current case describes anorexia nervosa. Females are 10 times more likely to be affected than males, and there is a higher incidence among those of upper to middle socioeconomic status. Anorexia nervosa has a 5 to 10 mortality rate.
Sexual abuse during childhood, especially incest, is linked to potentially devastating consequences in women that may not be recognized until middle age. These women may present with comorbidities of substance abuse, eating disorders, depression and other psychiatric conditions, as well as somatic symptoms, particularly chronic pelvic pain and gynecological complaints.39 The lifetime prevalence of PTSD is greater in women (12.5 ) than in men (6.2 ).38
Alcoholism is complicated by the fact that, particularly in women, it is often accompanied by other psychiatric disorders therefore, a holistic approach is required for treatment. Comorbid conditions include tobacco use, drug abuse, major depression, anxiety disorders, bulimia nervosa, and antisocial personality disorder (ASPD).4 Alcohol problems predict the subsequent use of tran-quilizing drugs in older women.5 Severe alcoholism, impulsivity, and suicidal tendencies also tend to coexist but are more likely to group in men.6 ASPD and antisocial symptoms are more prominent in male alcoholics, whereas in women alcoholism is often associated with anxiety (particularly social phobia) and affective disorders.4 Major depression is much more common in women than in men, and many studies have shown that antecedent depression is a risk factor for problem drinking. In women, there is a strong relationship between depression and smoking depressed individuals are more likely to smoke and are...
A 6yearold presents with a swollen 3x5cm tender erythematous anterior cervical neck node He denies fever weight loss
Small red papules occur at the site of inoculation, appearing in linear fashion similar to a cat scratch. Chronic regional lymphadenitis is characteristic, and tender nodes are usually evident in 1-4 weeks. The affected lymph nodes usually remain enlarged for approximately 2 months. The patient may be febrile and have associated symptoms such as headache, anorexia, and malaise. Parinaud occuloglandular syndrome (unilateral conjunctivitis, preauricular lymphadenopathy, and cervical lymphadenopathy) after rubbing the eye with the hands after cat contact is an atypical presentation.
Eating disorders affect BMD because the inability to maintain normal body mass promotes bone loss. The body-weight history of women with anorexia nervosa has been found to be the most important predictor of the presence of osteoporosis as well as the likelihood of recovery.8 The BMD of these patients does not increase to the normal range, even several years after recovery from the disorder. All individuals with a history of an eating disorder remain at high risk for osteoporosis in the future.
Constitutional symptoms are a common manifestation of fever, anorexia, malaise, headache, and myalgia The first two have clear effects on the nutritional status of the host. The hallmark sign of infection, fever, is induced by the release of interleukin-1 (IL-1), IL-6, and tumor necrosis factor-a (TNF-a), which act at the level of the hypothalamus to alter the temperature set point. This host response is believed to be a favorable adaptive response, but it comes at a substantial metabolic cost. For the augmentation of body temperature by 1 C, the basal metabolic rate increases by 12 to 23 .105 Therefore, with a fever of 40 C, the basal metabolic rate increases approximately 30 to 60 over baseline needs. Fever is generally accompanied by anorexia. Although the reason for this host response is not clear, its effects can be important. In a well-controlled study in Bangladesh, 41 children with diarrhea between 6 and 35 months of age and an age-matched control group were studied. It was...
Serotonin modulates numerous autonomic functions. It acts through the activation of a large family of G-protein-coupled-receptor subtypes that are widely expressed throughout the brain. The complexity of this signaling system and the paucity of selective drugs have made it especially difficult to define specific roles for 5-HT-receptor subtypes. Mutant mice lacking functional 5-HT2C receptors have been generated to elucidate the physiological function of this widely expressed receptor (156,157). Unexpectedly, 5-HT2C receptor-deficient mice display substantial overweight as a result of increased appetite. This obesity is characterized by leptin and insulin resistance, impaired glucose tolerance, and increased responsiveness to high-fat feeding. Thus, these mutant mice have established a role for the 5-HT2C receptor in the serotonergic control of feeding and energy expenditure. These findings also demonstrate a dissociation of serotonin and leptin signaling in the regulation of feeding,...
The second question is whether the depression is complicated by other disorders such as behavioural problems. If it is, then as a general rule it is best to sort out these complications before embarking on treatment for the depression. For example, if a child has a major behavioural disorder, then it will be necessary to ensure that appropriate psychosocial measures are being taken to deal with this. Similarly, the depression-like states that are common in adolescents with anorexia nervosa usually respond much better to weight gain than they do to antidepressants.
This stage is usually associated with headache, anorexia, nausea and vomiting, chills, fever, aches and pains, malaise, and a tender liver. There may also be fatigue and an upper respiratory flu-like infection. Those patients who smoke may develop a distaste for tobacco. b. Icteric. The jaundice appears and lasts for about 2 weeks. The body temperature often returns to normal but anorexia and nausea remain. There is usually dark urine and grayish stools. The liver remains tender and perhaps enlarged. The patient experiences flatulence and may have mild pruritis.
Preicteric Characterized by headache, anorexia, nausea and vomiting, chills, fever, aches and pains, malaise, and tender liver. Icteric Jaundice appears and stays approximately 2 weeks temperature returns to normal, but anorexia and nausea remain dark urine and grayish stools, liver remains tender and may be enlarged. (para 4-7a, b)
Legionnaires' disease may be mistaken for Pon-tiac fever, another manifestation of legionellosis. Both diseases initially present with anorexia, malaise, muscle pain, and headache. Legionnaires' disease is more serious than Pontiac fever since Pontiac fever is not associated with pneumonia or death. Patients with Pontiac fever tend to recover spontaneously within two to five days without treatment. Because both manifestations present with similar initial symptoms, health care practitioners must carefully assess any patient who exhibits legionellosis symptoms.
When the outcome was assessed in terms of mortality, major depression 10 and the symptoms of dissatisfaction, weight loss, anorexia and constipation, predicted higher mortality, which was not explained by the poor baseline somatic health of the depressed elderly. The mortality of dysthymic patients was also higher than that of nondepressed subjects, but this was explained by the high occurrence of physical diseases among them 11 .
Vegetative symptoms constitute the most biologically rooted clinical features of depressive disorders and are commonly used as reliable indicators of severity (severe depression with somatic symptoms in ICD-10 and melancholia in DSM-IV). They are manifested as profound disturbances in eating (anorexia and weight loss, or the reverse, bulimia and weight gain), in sleep (insomnia and or hypersomnia), in sexual function (decreased sexual desire or in a minority of cases the reverse), loss of vitality, motivation, energy and capacity to respond positively to pleasant events. Additionally, concomitant bodily sensations, usually diffuse pains, and complaints of fatigue and physical discomfort are reported. Disturbances of biorhythms are frequent and are considered as characteristic features of melancholia. They are mainly manifested in sleep patterns, predominantly with early morning awakening.
The specifying criteria for atypical depression, according to DSM-IV, are basically the reverse vegetative-somatic symptoms most commonly encountered in typical melancholia (i.e. hypersomnia instead of insomnia, hyperphagia and weight gain instead of anorexia and weight loss), while the mood is responsive to actual or potential positive events. Excessive sensitivity to rejection is also listed as a criterion. The symptoms have to predominate in the past recent 2 weeks of an episode of major depression or during the past 2 years of dysthymia. Although the validity of atypical depression has been frequently challenged in the past 58 , a recent review assessing published studies on the subject and applying Kendell's criteria for clinical validity concluded that atypical depression complies with two out of six validation criteria, the clinical description and the differential treatment response, monoamine oxidase inhibitors being more effective than tricyclics 59 .
Rates of violence and abuse do not differ for lesbian women. However, support groups specific to lesbian needs maybe lacking in specific communities. Alcohol and substance abuse and eating disorders maybe more prevalent among lesbian women.41 These issues can be equally as problematic for lesbian couples as they are for heterosexual couples. Little is known about lesbian or bisexual sexual health concerns. One might readily surmise that sexual concerns and difficulties do not differ from those of heterosexual women,
Symptomatic patients have fever, chills, asthenia, anorexia, productive cough and occasionally chest pain. These symptoms disappear in about 8 weeks. In about 5 of cases, a chronic infection develops with pulmonary infiltrates, pleural discharge, cavernous lesions and coccidioidomas. Disseminated forms of the disease affect most organs but predominantly the lymphatic nodes (colliquative form, Fig. 17.1), skin, bones, joints, liver, spleen, kidneys, the central nervous system, and occasionally the retina. Symptoms vary depending on the affected site. In the skin it can manifest as abscesses, fistulae, verrucous lesions, ulcers, and keloidal scars. Central nervous system involvement causes headache, confusion, hydrocephaly and diverse neurological syndromes. Differential diagnosis includes cancer, viral infections, Ricketts, mycoplasma, and mycobacteria infection, principally tuberculosis. It must also be distinguished from other mycoses, among them North American blastomycosis,...
Generally, adult tapeworms in the human intestine do not compete with the host for food substances therefore, the worms cause no symptoms. However, a heavy tapeworm infection may cause diarrhea, abdominal pain, and anorexia. Approximately 1 to 2 percent of those having fish tapeworm may develop anemia. Persons infected by the pork tapeworm sometimes have central nervous system involvement. In the central nervous system, cysticerci (the larvae of the pork tapeworm) are usually located in the meninges, cerebral cortex, ventricles, and occasionally the parenchyma. The symptoms, occurring several years after the infection, are brought on by the death of the larvae triggering inflammatory toxic reactions. The signs and symptoms are clear and can resemble those for cerebral tumor, basal meningitis, encephalitis, intracranial hypertension, and hysteria. The most prominent symptoms are those of recurrent epileptiform attacks.
The only categories of adverse events that differed between treatment group and placebo 109 . In routine clinical use, CNS side effects associated with selegiline may include sleep disturbance, psychosis, agitation, confusion, hypotension, anorexia and dyskinesias. Additionally, selegiline has the potential to interact with other drugs. Concurrent use of tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), or miper-idine should be avoided, as fatalities have been reported with these medication combinations 116-120 . Combining selegiline with bupropion has resulted in bupropion toxicity in animals, and the combination should be avoided 121 . In addition, combining selegiline and buspirone should be avoided because of the risk of hypertensive crisis 122 .
Furthermore, the adolescents also had a high comorbidity with other psychic and somatic disorders, for example, panic disorder (6.5 ), obsessive-compulsive disorder (27.4 ), simple phobias (33.8 ), eating disorder (4.3 ) and conduct disorder (24.2 ) 4 . Such a high comorbidity rate might result in considerable direct and indirect costs for society.
A 48-year-old female with a history of sarcoidosis comes to the ED with a chief complaint of syncope. She admits to anorexia, nausea, vomiting, and abdominal pain. She stopped going to work because she is too tired. Physical examination is significant for hyperpig-mented lesions and alopecia. Initial laboratory findings show a glucose level of 50 mg dL and a potassium level of 5.4 mEq L. What is the MOST likely diagnosis
She suffers from episodes of binge eating and self-induced vomiting ( BULIMIA). Postemetic rupture of the esophageal wall ( BOERHAAVE'S SYNDR.OMK) is usually seen following protracted and forceful vomiting of solid food it is common in alcoholics, bulimics, and pregnant women and in any condition that increases intra-abdominal pressure. The esophagus has three anatomic constrictions the cardiac (the most common site of rupture), the aortic arch, and the cricopharyngeal.
A 53-year-old woman presents with complaints of weakness, anorexia, malaise, constipation, and back pain. While being evaluated, she becomes somewhat lethargic. Laboratory studies include a normal chest x-ray serum albumin, 3.2 mg dL serum calcium, 14 mg dL serum phosphorus, 2.6 mg dL serum chloride, 108 mg dL BUN of 32 mg dL creatinine of 2.0 mg dL.
Function are contained within the technical manual, and a well-trained psychologist experienced with this test instrument should have no difficulty with interpretation. The clinical disorder scales deal with 20 DSM-IV diagnoses ADHD, conduct disorder, oppositional defiant disorder, adjustment disorder, substance abuse disorder, anorexia nervosa, bulimia nervosa, sleep disorders, somatization disorder, panic disorder, OCD, generalized anxiety disorder, social phobia, separation anxiety disorder, PTSD, major depression, dysthymic disorder, mania, depersonalization disorder, and schizophrenia. The personality disorder scales evaluate pervasive aspects of inner sense, feelings, affect, and thoughts, as well as behaviors that deviate significantly from normal characteristics of adolescence. The five personality disorder scales include avoidant personality disorder, obsessive-compulsive personality disorder, borderline personality disorder, schizotypal personality disorder, and paranoid...
Latency varies from several months to more than 10 years. The initial phase is characterized by fever, diarrhea, weight loss (wasting syndrome in 40-68 of cases), adenopathy, pruritus and other manifestations depending upon the level of cell-mediated immunosuppression. Many sexually transmitted diseases accompany AIDS gonorrhea, syphilis, hepatitis B, A, and non-A, non-B, pharyngitis, and chlamydial proctitis. In AIDS-related complex (ARC), neurologic or systemic illnesses appear, opportunist infections like oral candidiasis, multidermatomal herpes zoster, hairy cell leukoplasia, seborrheic dermatitis and retinal spots in cotton branches. Pre-existing dermatoses, like atopic dermatitis, psoriasis and Reiter's syndrome, deteriorate as the acquired immunodeficiency syndrome becomes increasingly severe. When AIDS is established, the following can appear Kaposi's sarcoma (7-50 ) (Fig.58.1), Hodgkin's disease and non-Hodgkin-lymphoma, Pneumocystis carinii pneumonia (74 ) that presents on...
After the Middle Ages, wine was prescribed constantly 'the astringent red wines for diarrhoea, the white wines as diuretics, port in acute fevers and for anaemia, claret and burgundy for anorexia, champagne for nausea and catarrhal conditions and port, sherry and madeira in convalescence' (Burke 1984, p. 200).
ID CC An 18-year-old white female presents with a malar rash that is exacerbated by sun exposure PHOTOSENSITIVITY) as well as with arthralgias and joint stiffness involving her ankles, wrists, and knee joints she also complains of decreased visual acuity, anorexia, weight loss, malaise, and weakness.
To diagnose sexual abuse it is important for the physician to perform a detailed history and physical examination. The patient may present to the physician with any number of complaints. Some examples of complaints that may be associated with sexual abuse are genital infections, genital or anal trauma, recurrent urinary tract infections, enuresis, encopresis, and inappropriate sexual behavior. The child may have other complaints such as sleep disorders, anxiety, phobias, fire setting, drug abuse, and eating disorders. In some instances the child tells her mother or a friend that she has been sexually abused.
CNS stimulation gives psychic effects of alertness, euphoria, increased concentration, increased mental performance (but only for simple tasks), increased physical performance (but not aerobic power), but also anorexia, headache and confusion. MDMA (Ecstasy) prompts abnormal behaviour, such as marathon dancing, especially when taken by a group (aggregation toxicology) as at 'rave' parties.
Localized adenopathy, especially in the cervical or supraclavicular region, is the most common presenting symptom. A mediastinal mass is often present. The presentation varies with the extent of the disease. Manifestations may include night sweats, fever, weight loss, lethargy, anorexia, and pruritus.
Metformin vs placebo can lower total cholesterol by up to 5 , triglycerides by 16 , and low-density lipoprotein (LDL) by 8 , with modest increases in high-density lipoprotein (HDL) of 2-5 . These values are not significantly changed when used in combination with sulfonylureas. The major adverse effects of metformin are gastrointestinal, including abdominal bloating, cramping, diarrhea, anorexia, and nausea, being reported in 20-30 of patients. These adverse effects are usually mild and can occasionally be mitigated by taking the medication with food.
A 19-year-old male presents with a 1-week history of malaise and anorexia followed by fever and sore throat. On physical examination, the throat is inflamed without exudate. There are a few palatal petechiae. Cervical adenopathy is present. The liver is percussed at 12 cm and the spleen is palpable.
Although alcoholism, major depression, and anxiety disorders often occur together in women, there is not much overlap in the genes underlying these disorders. Seventy-five percent of the genetic liability to alcoholism is disease-specific, and only small genetic components for alcoholism load on to a genetic factor common to major depression and generalized anxiety disorder as well as a factor common to phobia, panic, and bulimia nervosa.21
A thorough physical examination is important for the same reasons. Lid lag and or enlargement or nodularity of the thyroid suggests hyperthyroidism. Moon facies, thin skin, and a buffalo hump suggest hypercortisolism. Cachexia mandates screening for an eating disorder or malignancy. A pelvic examination is one aspect of the total evaluation of hormonal status and a necessary part of the physical examination in women. Osteoporotic fractures are late physical manifestations. Common fracture sites are the vertebrae, forearm, femoral neck, and proximal humerus. The presence of a dowager's hump in elderly patients indicates multiple vertebral fractures and decreased bone volume.
Other illnesses likely to shape the course of depressive symptoms and effectiveness of treatment include stimulant or opiate dependence, somatization disorder, obsessive-compulsive disorder, antisocial personality disorder and anorexia nervosa. While a careful history, and the interview of informants, will often uncover important, pre-existing conditions, the following should increase suspicion that another disorder underlies the depressive symptoms for which the patient is seeking help. The inability to clearly identify an episode onset is foremost among these. A simple question as to when the patient last experienced two or more months without depressive symptoms will reveal a chronic mood disorder in many patients. Even if further investigation reveals no additional underlying disorder, knowledge that symptoms are longstanding has powerful prognostic significance. In a similar vein, the tendency of a patient to view depressive symptoms as characteristic of his or her normal self is...
We have all been there: turning to the refrigerator if feeling lonely or bored or indulging in seconds or thirds if strained. But if you suffer from bulimia, the from time to time urge to overeat is more like an obsession.