Core Messages

• Allergic conjunctivitis is inflammation of the ocular surface with IgE, cells, cytokines and mediators

• Several chemokines/adhesion molecules, cytokines and neuropeptides are detectable in situ in allergic conjunctival tissues

• Growth factors, and mainly nerve growth factor (NGF) and transforming growth factor pi (TGF-p1),are also found to be increased in the blood, tears and tissues of patients with allergic conjunctivitis

• A significant correlation is observed between plasma levels of NGF and the increased number of mast cells (MCs) and eosinophils (EOSs) in the tarsal and bulbar vernal keratoconjunctivitis (VKC) conjunctiva

• Fibrosis can be observed in the conjunctiva of VKC (giant papillae formations) as a consequent manifestation of allergy

• Overproduction and deposition of collagens and tissue remodelling in VKC may be due to imbalance of matrix metallopro-teinases and their physiological inhibitors

• Various growth factors (NGF,TGF-p1) and cytokines, produced by both inflammatory and stromal cells, have been proposed to cause tissue repair

• VKC and atopic keratoconjunctivitis (AKC) diseases can compromise the cornea, with ulcers and scarring ultimately leading to visual loss

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

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