Summary for the Clinician

• An immune-complex mediated microangiopathy or vasculitis may play a role in the pathogenesis of scleritis

• The higher levels of complement Ci and ability of induced scleral fibroblasts to increase production of complement components may be involved in the inflammatory cascade, resulting in inflammatory cell infiltration, fibrinoid necrosis, and vascular occlusion

• The role of a cell mediated delayed hyper-sensitivity reaction is supported by the increase in T-lymphocyte helper to suppressor ratio in scleritis

• Aberrant HLA-DR expression in scleritis may play a role in the altered immune function in these patients

• The pathologic findings of scleritis can have characteristic features based upon the aetiology and be classified as rheumatoid, idiopathic, postinfectious, and sarcoidal

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

Get My Free Ebook


Post a comment