Summary for the Clinician

• A basic function of MALT is the immune regulation at mucosal surfaces by balancing between an inflammatory immune defence of pathogens and a tolerance of the ubiquitous non-pathogenic antigens

• The preference is for a generation of tolerance mechanisms in order to avoid constant inflammatory destruction of the delicate mucosal surface

• Immune regulation is mainly performed by a special class of professional antigen presenting cells, dendritic cells (DC)

• Depending on external influences in the tissue (cytokine milieu, microbes, cell wounding, etc.), the function of DC is biased and leads to the stimulation of different types of T-helper (Th) cells that govern different directions of immune response by differential patterns of secreted immunomodulatory mediators (cytokines)

• Th1-lymphocytes maintain inflammatory defence, Th2 cells stimulate the mainly anti-inflammatory immunoglobulin production and Th3 (or regulatory T cells) act immuno-suppressively

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

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