Median rhomboid glossitis (figure 2-9) appears as a smooth, flat, depressed or elevated nodular area on the dorsum of the tongue just anterior to the circumvallate papillae. It is usually an oval or diamond-shaped area and stands out because the area has no filiform papilla. Median rhomboid glossitis is believed to be caused by a Candida infection, often with secondary hyperplasia. Treatment may include the use of an antifungal drug and surgical removal of the hyperplastic tissue.
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