Drug Pipelines

A dynamic drug portfolio is the fuel that propels pharmaceutical companies forward. Through organic growth and in-licensing of worthy compounds, pharmaceutical companies are able to launch new products to the market. Pipeline databases allow users to track, analyze, and monitor the drugs being developed by competitors and to identify products for in-licensing and alliances. The databases offer numerous points of access, including a drug's name, generic name, and mechanism of action. Structure and sequence searching is also available. Some producers include financial data from analysts who have a vested interest in how the drug will perform in the market when launched.

Users of pipeline databases include pharmaceutical and biotech companies, who assess their own position and that of their competitors by using the databases as a source of benchmark measures. Brokerage firms use the databases to make informed assessments of companies in their portfolios. Academic institutions can use the databases to look for possible partners for compounds in their research laboratories.

Adis R&D Insight. Adis International, 770 Township Line Road, Yardley, PA 10967, U.S.A. Phone: +1 267-757-3400. URL: http://www.adis.com. Adis International, a division of Wolters Kluwer, offers a number of resources for tracking and evaluating drugs in development. Adis R&D Insight currently has profiles of more than 19,000 drugs in development including drugs in both the clinical and discovery phase. In addition to a literature review of published clinical data, the database also includes a proprietary evaluation of the drug's therapeutic value and commercial potential from Lehman Brothers. The database is available via the Internet (http:// www.biadisinsight.com), extranet, CD-ROM, Lotus Notes, and online. Custom data feeds are available.

IMS R&D Focus. IMS Health, 660 West Germantown Pike, Plymouth Meeting, PA 19462-0905, U.S.A. Phone: +1 610834-5000. URL: http://www.ims-global.com. IMS's pipeline database, R&D Focus, covers approximately 8500 drugs in development from preclinical through launch. The database is part of the IMS Lifecycle collection of databases. This collection includes New Product Focus, which covers launched drugs and Patent Focus, which covers the patent status of compounds. The product is available via an Internet subscription, CD-ROM or online. Customized licenses are available upon request.

Investigational Drugs Database (IDdb). Thomson Scientific, 14 Great Queen Street, London WC2B5DF, U.K. Phone: +44-20-7344-2800. URL: http://scientific.thomson.com. North American contact: 3501 Market Street, Philadelphia, PA

19104, U.S.A. Phone: +1 800-336-4474, Fax: +1 215-386-2911. E-mail: [email protected]. Current Drugs, a division of Thompson Scientific, produces the Investigational Drugs Database (IDdb). IDdb covers the R&D portfolios of over 15,000 public and private companies, institutes and universities. The database includes drugs from first patent submission to launch. Each record contains detailed information from published clinical trials, patents, scientific conferences and meetings, and commercial publications. Commercial potential reports are included if available. The database is available via Internet subscription (http://www.iddb.com/).

NDA Pipeline. FDC Reports, 5550 Friendship Blvd., Suite. 1, Chevy Chase, MD 20815-7278, U.S.A. Phone: +1 301-665-7157, Fax: +1 301-656-3094, E-mail: [email protected] com. URL: http://www.fdcreports.com. FDC Reports, a division of Elsevier has published the annual The NDA Pipeline for 20 years and has recently produced an electronic database version. The database, which can be found at http://www.ndapipeline.com, is updated weekly and allows the user to monitor drug development throughout the clinical trial process. The database is available through Internet subscription and online.

PharmaProjects. PJB Publications, 69-77 Paul Street, London EC2A4LQ, U.K. Phone: + 44-20-7017-6861. URL: http://www. pharmaprojects.co.uk. North American contact: Pharma-Books, 270 Madison Ave., New York, NY 10016, U.S.A. Phone: + 1 212-520-2781. PharmaProjects, produced by PJB Publications, contains over 34,800 drug records and dates back to 1980. The database is available on CD-ROM, Internet subscription, and online. PJB can also provide customized feeds via direct delivery and for Lotus Notes applications.

Prous Science Integrity. Prous Science, Provenza, 388 08025 Barcelona, Spain. Phone: +34-93-459-22-20, Fax: +34-93458-15-35. E-mail: [email protected]. URL: http://www. prous.com. North American contact: Prous Science, 1500 Market Street, East Tower, 12th Floor, Philadelphia, PA 19102, U.S.A. Phone: +1 215-246-3441, Fax: +1 215-2463496. E-mail: [email protected]. Prous's Integrity database is an integrated drug discovery and development portal, which covers all areas of discovery and development. Users query the database using structure and sequence searching capabilities as well as drug name. Prous also publishes several journals covering drugs in development, including Drug News & Perspectives, Drug Data Report, Drugs of the Future, and Drugs of Today. A subscription-only news service, Daily-DrugNews.com, compiles news and other resources on drugs in development as well as launched products. The Integrity database is available by Internet subscription (http://integrity.prous. com), and several of the Prous sources are available online.

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