Diabetic Glomerulosclerosis

ID/CC

HPI PE Labs

Imaging Gross Pathology Micro Pathology

Treatment Discussion

A 22-year-old white male complains of recurrent episodes of "bloody urine" that lasted for several days in conjunction with a URI.

He was well until the onset of symptoms. Pallor; slight palpebral edema.

UA: proteinuria; red cell casts in urine; gross hematuria. Increased serum IgA.

Focal glomerulonephritis involving only selected glomeruli with mesangial proliferation and segmental necrosis with crescents; IgA deposits with some IgM, IgG, and C3 on immunofluorescence.

Supportive.

Idiopathic but associated with upper respiratory or GI infections lacking a latency period {vs. poststreptococcal glomerulonephritis). The glomerular pathology seen in Berger's disease is similar to that seen in Henoch-Schonlein purpura, which is seen in children. Chronic renal failure may ultimately develop. ^^JyjjJjj p.250

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Alcohol No More

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