Diabetic Glomerulosclerosis



Imaging Gross Pathology Micro Pathology

Treatment Discussion

A 22-year-old white male complains of recurrent episodes of "bloody urine" that lasted for several days in conjunction with a URI.

He was well until the onset of symptoms. Pallor; slight palpebral edema.

UA: proteinuria; red cell casts in urine; gross hematuria. Increased serum IgA.

Focal glomerulonephritis involving only selected glomeruli with mesangial proliferation and segmental necrosis with crescents; IgA deposits with some IgM, IgG, and C3 on immunofluorescence.


Idiopathic but associated with upper respiratory or GI infections lacking a latency period {vs. poststreptococcal glomerulonephritis). The glomerular pathology seen in Berger's disease is similar to that seen in Henoch-Schonlein purpura, which is seen in children. Chronic renal failure may ultimately develop. ^^JyjjJjj p.250

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Alcohol No More

Do you love a drink from time to time? A lot of us do, often when socializing with acquaintances and loved ones. Drinking may be beneficial or harmful, depending upon your age and health status, and, naturally, how much you drink.

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