Medical

7. Metastasis a. Initial routes of metastasis i. Lymphatic spread is the most common route of spread for epithelial carcinomas ii. Hematogenous spread

• Most sarcomas

• Renal cell carcinoma

• Hepatocellular carcinoma

• Follicular carcinoma of the thyroid

• Choriocarcinoma iii. Seeding of body cavities and surfaces, as in ovarian carcinoma iv. Transplantation via mechanical manipulation (e.g., surgical incision, needle tracts) may occur but is relatively rare

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