Review Questions

1. A 16-year-old girl comes to the physician because of a "large growth" on her earlobe. She says that she began to notice it about 3 weeks after she got her ears pierced, and it has been growing "exponentially" ever since. Physical examination shows a 3-cm, firm tumor hanging from her left earlobe. Excessive production of which of the following types of collagen is associated with this condition?

2. A wealthy 87-year-old woman comes to the physician because of 3-week history of "bleeding gums." She says that her gums have always been "a bit sensitive," but they now they bleed whenever she eats something hard or when she brushes her teeth. Her cook passed away 6 months ago, and she has been eating "tea and toast" ever since. Physical examination shows erythematous, inflamed gums. Which of the following is the most likely diagnosis?


Ehlers-Danlos syndrome


Marfan syndrome


Osteogenesis imperfecta





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