Review Questions

Serum Iron Total Iron

% Saturation

Serum Ferritin

Binding Capacity

A. Decreased Decreased

B. Decreased Decreased

C. Decreased Increased

D. Decreased Increased

E. Increased Decreased E Increased Decreased

Increased

Increased

Decreased

Decreased

Increased

Increased

Decreased

Increased

Decreased

Increased

Decreased

Increased

2. A 14-year-old girl is brought to the emergency department by a camp counselor because of severe leg pain. She knows that she has a "chronic disease," but she is not exactly sure what it is. Physical examination shows a 2-cm ulcer on her lower leg that appears to extend to the bone. An x-ray of her lower leg is normal. A technetium radionuclide scan of her leg shows increased uptake. Cultures of the wound grow Salmonella. A peripheral blood smear shows Howell-Jolly bodies. Which of the following is the most likely underlying condition?

A. Alpha-thalassemia

B. Beta-thalassemia

C. G6PD-deficiency

D. Hereditary spherocytosis

E. Sickle cell anemia

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