Review Questions

1. An 18-year-old college student comes to the student health clinic because of an 8-h history of a severe headache and "stiff neck." She says that two other students In her dormitory have similar symptoms. Her temperature is 39.3°C (102.8°F). Physical examination shows nuchal rigidity and palpable purpura on her trunk and lower extremities. Gram stain analysis of cerebrospinal fluid obtained by a lumbar puncture shows Gram-negative intracellular diplococci. Which of the following types of inflammation is most likely associated with this patient's neurologic condition?

A. Cytopathic inflammation

B. Exudative inflammation

C. Granulomatous inflammation

D. Interstitial inflammation

E. Necrotizing inflammation

2. A 69-year-old woman comes to the emergency department because of a 7-d history of fever, cough, chills, and pleuritic chest pain. She says that her sputum was initially a rust color, but it has been more yellowish over the past few days. Diffuse rales are heard on auscultation. A chest x-ray shows patchy infiltrates. A Gram stain of a sputum sample reveals Gram-positive diplococci. Which of the following is the most likely tissue response to this infectious organism?

A. Acute inflammatory response with neutrophils

B. Cell killing by cytotoxic T lymphocytes

C. Diffuse mononuclear interstitial infiltrate

D. Granulomatous inflammation with lymphocytes and macrophages

E. Severe tissue damage and extensive cell death

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