Diabetes Prevention Study

The Diabetes Prevention Study involved 3234 patients with IGT and BMI greater than 24 kg/m2. There were three groups for assignment: placebo, metformin (850 mg twice daily), or intensive lifestyle changes. The lifestyle modifications included dietary instruction, 150 minutes of exercise weekly, and a calorie-restricted, low-fat diet. These patients were followed for an average of 2.8 years. The study demonstrated a 58% relative risk reduction in progression to diabetes with diet and exercise compared with a 31% relative risk reduction with metformin. The number of patients needed to treat was seven for 3 years for lifestyle modification and 14 for metformin. The metformin seemed to be more effective in the younger patients with higher BMI and higher fasting-glucose levels than in patients more than 60 years of age, who showed the least benefit with the drug (14).

Delicious Diabetic Recipes

Delicious Diabetic Recipes

This brilliant guide will teach you how to cook all those delicious recipes for people who have diabetes.

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