• Formal investigations usually not required

• An accurate record must be made of the number, size, location, and consistency of penile plaques

• Indications for formal assessment include—

■ Presence of complex deformities

■ If surgery is being considered

■ Monitoring of medical therapy

■ Persistence of diagnostic doubt

■ As part of a research protocol

Advanced investigations for Peyronie's disease are summarized in Table 12.3.

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