Normally found in muscle, liver, heart, kidney, brain May be only marker elevated in seminoma Correlates with tumor burden Poor specificity

Five isoenzymes (LD1 most testis specific)


<1.5 times upper limit of normal

<109IU/L (for LD1)

2.8 days

May be produced by virtually any tumors Myocardial infarction, cardiac failure, anemia, pulmonary embolism Hemolysis of blood sample

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