Prevention of PAD

A post-hoc analysis of the Scandinavian Simvastatin Survival Study (4S) found that new or worsening intermittent claudication was significantly (p = 0.008) reduced (by 38%) in those taking the statin when compared with the group assigned to placebo [30]. All the patients (n = 4444) participating in this trial had CHD and were fol-lowed-up for a median of 5.4 years.

In the Program on the Surgical Control of Hyperlipid-emias (POSCH) [9] the effect of cholesterol-lowering induced by partial ileal by-pass in patients (n = 838) with a previous MI and hyperlipidaemia was assessed. The incidence of new cases of claudication was significantly lower [relative risk (RR): 0.66, 95% confidence interval (CI): 0.20-0.90; p = 0.009] in the intervention group when compared with the control (nonintervention) group 4 years after the closure of the trial.

Was this article helpful?

0 0
Lower Your Cholesterol In Just 33 Days

Lower Your Cholesterol In Just 33 Days

Discover secrets, myths, truths, lies and strategies for dealing effectively with cholesterol, now and forever! Uncover techniques, remedies and alternative for lowering your cholesterol quickly and significantly in just ONE MONTH! Find insights into the screenings, meanings and numbers involved in lowering cholesterol and the implications, consideration it has for your lifestyle and future!

Get My Free Ebook


Post a comment