CT colonography interpretation requires radiologists to create interactively two- and three-dimensional images of the colonic lumen, use a variety of window and level settings, and compare supine and prone three-dimensional datasets. Colonic datasets are interrogated systematically to screen for potential colorectal lesions, employing well-established problem-solving techniques at the computer workstation to distinguish true neoplasms from benign and normal structures. A visual understanding of the normal appearance of colorectal structures, benign lesions, disease mimics and colorectal neo-plasia is necessary in utilizing the capabilities of modern CT colonography computer workstations to accurately diagnose disease.
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