False Positive and False Negative Diagnosis

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Most studies using low dose CT without IV contrast report upon hepatic or renal cysts that were further evaluated. False positives are thus caused by a low dose technique without IV contrast. For example, in the study of Hellstrom et al. (Hellstrom et al.

2004), there were four false positives: two cases of renal cysts, one normal pancreas, and one case of focal fatty infiltration. The contrary is reflected in the results of the study of Spreng et al. (Spreng et al.

2005), and focus on the group of patients with normal dose CT after IV contrast: in this single study no false positives were caused by renal or hepatic cysts. The

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