CT colonography (Virtual Colonoscopy) has rapidly evolved since its initial description just over a decade ago. It has gradually moved from being a research tool that was largely confined to academic teaching hospitals to a clinical test that is now widely available in many community-based hospitals. With its potential to become a credible tool for colon cancer screening many radiologists are interested in establishing CT colonography in their departments, physicians are requesting the test more frequently and, increasingly, patients are demanding it. The following chapter examines the essential components, minimum requirements and potential hurdles in establishing an effective CT colonography service in a busy diagnostic radiology department.

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