As with faecal tagging more residue can be left over in the colon without decreasing the accuracy of polyp detection, performing CT colonography after a preparation without cathartic cleansing is the obvious next step. Indeed, eliminating the need for cathartic cleansing prior to CT colonography would dramatically increase the adherence of an asymptomatic patient population to a colon cancer screening program (Rex 2000). This method has been called laxative-free CT colonography (Lefere et al. 2004). Several methods have been developed. These methods are based upon faecal tagging and are still at the research stage. A truly prepless method (i.e. no diet, no faecal tagging and no cathartic cleansing) has not yet been developed.

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