Pineau et al. (2003) conducted a comparative study with optic colonoscopy assessing the diagnostic accuracy of virtual colonoscopy using oral contrast. The colonography examination was done with a primary 2D method with 3D problem solving. In a population of 205 patients the sensitivity for large (>10 mm) colorectal polyps was 78%. The reported specificity was higher (95%). This decreased for medium-sized (6-9 mm) polyps to 75 and 83% respectively.
Johnson et al. (2003b) conducted a multi-center accuracy study (18 radiologists) with a primary axial 2D method with MPR and 3D for problem solving. The average sensitivity for large polyps was 75% with a corresponding specificity of 73%, for polyps >6 mm these figures were 54 and 72% respectively. Experienced readers performed better.
Iannaccone et al. (2004b) used a primary axial 2D method for detection of colorectal polyps in a partly symptomatic population of 203 patients. Patients had not been cathartically prepared but oral contrast was added to a low fiber diet, two days prior to the colonography examination. The average sensitivity per polyp for three observers was 100% for large polyps and 86% for polyps >6 mm. Specificity per patient was 100% for large polyps and 94% for polyps >6 mm.
These studies show that in a high prevalence population, primary 2D studies report good results for large polyps.
Was this article helpful?
Stop The Pain. Manage Your Diverticular Disease And Live A Pain Free Life. No Pain, No Fear, Full Control Normal Life Again. Diverticular Disease can stop you from doing all the things you love. Seeing friends, playing with the kids... even trying to watch your favorite television shows.