Use of both supine and prone data sets of a patient is important for improving the specificity in the detection of polyps, because the mobility of a suspicious lesion between supine and prone views can differentiate polyps from stool (Chen et al. 1999; Morrin et al. 2002). A real polyp tends to stay at the same location in the supine and prone views of the colon, whereas a piece of stool tends to move around in the colon, and thus, the stool can be found in different locations when supine and prone views are compared.
However, in order for CAD to find such movement, it is necessary to establish a location correspondence between the supine and prone views. This is often a challenging task because the colon can be substantially deformed when the patient's position is changed from supine to prone. Moreover, some parts of the colon can be displaced and collapsed at this positional change.
Most of the previous studies on correspondence between the supine and prone views were aimed
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