Ab

Figure 38 Dermatofibrosarcoma protuberans. (A) The lesion is arising from the inner left labia minora. (B) An important clue to the nature of this bland-appearing spindle cell lesion is its infiltrative nature, as seen in this subcutaneous adipose tissue.
Table 38 Dermatofibrosarcoma Protuberans

Clinical

Differential

Diagnosis

Symptoms

appearance

diagnosis

Therapy

Dermatofibrosarcoma

Mass, ulceration,

Red, brown, or

Benign fibrous

Wide local

protuberans

pain, bleeding

flesh-colored

histiocytoma,

excision

nodules (70)

dermatofibroma

from mineralization of phagocytosed material (78). A relationship to Escherichia coli infection is frequent. Immune dysfunction has been postulated as an etiology (Table 42) (79).

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