A variety of vulvar conditions are associated with pigmentation abnormalities. Visual examination can help to identify abnormalities at an early disease stage. Vulvar self-examination is important, allowing patients to benefit from early disease diagnosis. Removal of abnormal and changing vulvar lesions for histologic evaluation is of utmost importance. When vulvar melanomas are identified in patients, they should be referred to centers experienced with this disease process. A multidisciplin-ary approach to treating and following these patients is required for optimal care and outcomes. Vulvar melanoma behaves biologically similarly to cutaneous melanoma with similar prognostic factors. An important goal is to improve knowledge and facilitate grouping of cases from different institutions to optimize diagnosis and treatment regimens for patients with vulvar melanoma.

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