For a full account, readers are referred to the recent monograph by van der Putte (18). Ovaries
Primordial germ cells migrate to the genital ridge to form the gonads. In the fifth-week, the gonads are indifferent and capable of developing into testes or ovaries (19). Gonadal differentiation is achieved through a complex interaction between different expressed genes. The genetic expression of genes on the Y chromosome, particularly SRY, the master regulatory gene, causes the gonad to become a testis. The first sign of testicular development is the presence of Sertoli cells at six to seven weeks. Ovarian development is thought to be related to expression of Dax-1 (20). The first primordial ovarian follicles are seen after 13.5 weeks.
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Complete Guide to Preventing Skin Cancer. We all know enough to fear the name, just as we do the words tumor and malignant. But apart from that, most of us know very little at all about cancer, especially skin cancer in itself. If I were to ask you to tell me about skin cancer right now, what would you say? Apart from the fact that its a cancer on the skin, that is.