Interlabial Sulcus

The interlabial sulcus is the main site of mammary-like glands (12). Mammary-like glands are a newly described type of skin appendage confined to the anogenital region. They open by ducts into the interlabial sulcus, and to a lesser extent, perineal and perianal skin. Vulvar mammary-like glands resemble eutopic mammary lactiferous ducts and glands with diverticula, branches, lobules, and the expression of estrogen and progesterone receptors (Figs. 6 and 7). They may also show apocrine metaplasia and some features of eccrine glands. Hidradenoma papilliferum and mammary conditions of the vulva (ectopic breast, ectopic breast tissue, fibroade-noma, phyllodes tumor, and primary breast-like adenocarcinoma) appear to be derived from mammary-like glands (12,13).

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