This rare dermatosis occurs most frequently on the genital skin and lower abdomen. The distinctive eruption consists of an erythema with erosions, vesiculation, and bulla formation. The rash extends outward with healing and crusting at the outer edge. Postinflammatory pigmentation is common. There is also an associated weight loss, glossitis, and angular cheilitis. The patient may also have diabetes. Histologi-cally, there is marked epidermal necrolysis and a mild dermal lymphocytic infiltrate. It is nearly always associated with an underlying pancreatic glucagonoma. The dermatosis resolves with treatment of the glucagonoma and correction of nutritional deficiencies secondary to malabsorption (Table 15).
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.