Medical

Proliferative phase

The proliferative phase is estrogen dependent. It corresponds to the preovulatory period of follicular maturation. Ovulation normally occurs at the end of the proliferative phase, 14 days before menstruation begins—usually between the 10th and 14th day.

Secretory phase

The secretory phase is progesterone-dependent and associated with the luteal phase of the ovary.

No fertilization

■ The corpus luteum degenerates 12 days after ovulation.

• A drop in progesterone and estrogen levels ensues.

• The functional layer degenerates and menstrual flow commences.

Fertilization

Uterine changes in relation to fertilization (see Weeks 1 and 2 in Embryology section),

Anterior pituitary

Follicle stimulating )

hormone (FSH)

Proliferative phase Secretory phase

Figure 1-10-3. Menstrual Cycle

Proliferative phase Secretory phase

Figure 1-10-3. Menstrual Cycle

KAPLAN- , medical 83

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