1 Foulds, L. (1954) Tumor progression. Cancer Res. 17, 337-339

2. Foulds, L. (1969) Neoplastic Development. Academic, New York

3. Nowell, P. C. (1986) Mechanisms of tumor progression. Cancer Res. 46,22032207.

4. Weinberg, R. A. (1989) Oncogenes and multistep carcinogenesis, in Oncogenes and the Molecular Origin of Cancer (Weinberg, R. A., ed), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 307-326.

5. Cairns, J. (1981) The origins of human cancers Nature 269, 346-348.

6. Folkman, J. and Klagsbrun, M. (1987) Angiogenic factors. Science 235, 442-447

7. Nicholson, G. L. andMilas, L. (eds.) (1984) Cancer Invasion and Metastasis: Biologic and Clinical Aspects. Raven, New York.

8. Tooze, J. (ed.) (1981) Molecular Biology of Tumor Viruses, 2nd ed., Rev., DNA Tumor Viruses. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

9. Hanahan, D. (1988) Dissecting multistep tumongenesis in transgenic mice. Ann. Rev. Genet. 22,479-519.

10. Hanahan, D. (1989) Transgenic mice as probes into complex systems. Science 246,1265-1275.

11. Cavanee, W., Hastie, N„ and Stanbndge, E. (eds.) (1989) Recessive Oncogenes and Tumor Suppression. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

12. Weiss, R., Teich, N„ Varmus, H„ and Coffin, J. (eds.) (1984) Molecular Biology of Tumor Viruses, 2nded., RNA Tumor Viruses, Part 1, Text. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

13. Weiss, R.,Teich, N„ Varmus, H„ and Coffin, J. (eds.) (1985) Molecular Biology of Tumor Viruses, 2nd ed., RNA Tumor Viruses, Part 1, Supplements and Appendixes. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

14. Bishop, J. M. (1984) Cellular oncogenes and retroviruses. Ann Rev. Biochem. 52, 301-354.

15. Nusse, R. and Berns, A. (1988) Cellular oncogene activation by insertion of retroviral DNA. Genes identified by proviral tagging, m Cellular Oncogene Activation (Klein, G., ed.), Marcel Dekker, New York, pp. 95-119.

16 Der, C. J , Krontins, T. G, and Cooper, G.M. (1982) Transforming genes ot human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses. Proc. Natl. Acad. Sci. USA 79,3637-3640.

17. Parada, L. F„ Tabin, C. J., Shih, C., and Weinberg, R. A. (1982) Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene. Nature 297, 474-478.

18. Santos, E., Tronick, S. A., Aaronson, S. A., Pulciani, S., and Barbacid, M. (1982) T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALAB- and Harvey-MS V transforming genes Nature 298, 343-347.

19. Bishop, J. M. (1987) The molecular genetics of cancer. Science 235,305-311.

20. Haluska, F. G, Tsujimoto, Y„ and Croce, C. M. (1987) Oncogene activation by chromosome translocation in human malignancy. Ann. Rev. Genet. 21,321-346.

21. Bishop, J. M. (1989) Oncogenes and clinical cancer, in Oncogenes and the Molecular Origin of Cancer (Weinberg, R. A., ed.), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

22. Weinberg, R. A (1985) The action of oncogenes in the cytoplasm and nucleus. Science 230, 770-776.

23 Eisenman, R N. (1989) Nuclear oncogenes, in Oncogenes and the Molecular Origin of Cancer (Weinberg, R A , ed), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

24. McCormick, F. (1989) ras Oncogenes, m Oncogenes and the Molecular Origin of Cancer (Weinberg, R. A., ed.), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

25. Land, H., Parada, L. F., and Weinberg, R. A. (1983) Tumorigenic conversion of primary embryonic fibroblasts requires at least two cooperating oncogenes Nature 304, 596-602.

26. Rassoulzadegan, M„ Nagashfar, Z., Cowie, A., Carr, A., Gnsoni, M., Kamen, R., and Cuzm, F. (1983) Expression of the large T protein of polyoma virus promotes the establishment m culture of "normal" rodent fibroblast cell lines. Proc. Natl. Acad. Sci. USA 80,4354-4358.

27. Ruley, H. E. (1983) Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature 304,602-606.

28. Stewart, T. A., Hollingshead, P. G„ and Pitts, S. (1988) Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis of fusion genes m transgenic mice. Mol. Cell. Biol. 8, 473-479.

29 Henrard, D. and Ross, S R. (1988) Endogenous mouse mammary tumor virus is expressed in several organs in addition to the lactating mammary gland. J Virol. 62, 3046-3049.

30. Nusse, R., Brown, A„ Papkoff, J., Scambler, P., Shackleford, G., McMahan, A., Moon, R„ and Varmus, H. (1991) A new nomeclature for int-1 and related genes: the Wnt gene family. Cell 64,231,232.

31. Stewart, T. A., Pattengale, P. K., and Leder, P (1984) Spontaneous mammary adenoarcmomas in transgenic mice that carry and express MTY/myc fusion genes. Cell 38, 627-637.

32. Leder, A., Pattengale, P. K„ Kuo, A., Stewart, T. A., and Leder, P. (1986) Consequences of widespread deregulation of the c-myc gene m transgenic mice: multiple neoplasms and normal development. Cell 47, 8-11.

33. Sinn, E„ Muller, W., Pattengale, P., Tepler, I., Wallace, R., and Leder, P. (1987) Cooexpression of MMTV/v-Ha-rav and MMTC/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo. Cell 49,465-475.

34. Tremblay, P. J., Pothier, F., Hoang, T., Tremblay, G.( Brownstem, S., Liszauer, A., and Jolicoeur, P. (1989) Transgenic mice carrying the Mouse Mammary Tumor Virus ras fusion gene: distinct effects in various tissues. Mol. Cell Biol. 9, 854-859.

35. Choi, R., Henrard, D„ Lee, I., and Ross, R. (1987) The mouse mammary tumor virus long terminal repeat directs expression in epithelial and lymphoid cells of different tissues of transgenic mice. J. Virol. 61, 3013-3019.

36. Kwan, H., Pecenka, V., Tsukamoto, A., Parslow, T. G., Guzman, R., Lin, TP., Muller, W. J., Lee, F. S., Leder, P., and Varmus, H. E. (1992) Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice. Mol. Cell Biol. 12,147-154.

37. Tsukamoto, A. S., Grosschedl, R., Guzman, R. C., Parslow, T., and Varmus, H. E. (1988) Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinoma in male and female mice. Cell 55, 619-625.

38. Muller, J. M., Lee, F S., Dickson, C., Peters, G., Pattengale, P., and Leder, P. (1990) The int-2 gene product acts as an epithelial growth factop in transgenic mice. EM BO J. 9, 907-913.

39. Iwamato, T., Takahashi, M , Ito, M , Hamaguchi, M„ Osobe, K„ Misawa, N.,

Asai, J., Yoshida, T., and Nakashimi, I. (1990) Oncogenicity of the ret transforming gene in MMTV/ref transgenic mice. Oncogene 5, 535-542.

40. Muller, W. J., Sinn, E., Pattengale, P. K„ Wallace, R., and Leder, P. (1988) Single step induction of mammary adenocarcinoma m transgenic mice bearing the activated c-neu oncogene. Cell 54, 105-115.

41. Brouchard, L., Lamarre, L., Tremblay, P. J„ and Jolicoeur, P. (1989) Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene. Cell 57, 931-936.

42. Mangues, R., Seidman, I., Pellicer, A., and Gordon, J. W. (1990) Tumongenesis and male sterility in transgenic mice expressing a MMTV/N-rai oncogene. Oncogene 5, 1491-1497.

43. Matsui, Y„ Halter, S. A., Holt, J. T„ Hogan, B. L. M„ and Coffey, R. J. (1990) Development of mammary hyperplasia and neoplasia in MMTV-TGFa transgenic mice. Cell 61, 1147-1155

44. van Lohuizen, M., Verbeek, S., Schejen, B., Wientjens,E., van der Gulden, H., and Berns, A. (1991) Identification of coopertatmg oncogenes in E|x-myc transgenic mice by provirus tagging. Cell 65,737-752

45. Haupt, Y„ Alexander, W. S., Barn, G., Klinken, S. P., and Adams, J. M. (1991) Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E|x-myc transgenic mice. Cell 65, 753-763.

Was this article helpful?

0 0

Post a comment