References

1. Evans, M. J. and Kaufman, M. H. (1981) Establishment in culture of plun-potential cells from mouse embryos. Nature 292, 154-156.

2. Martin, G. R. (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Nat. Acad. Set. USA 78, 7634-7638.

3. Bradley, A., Evans, M., Kaufman, M. H., and Robertson, E. (1984) Formation of germ-line chimeras from embryo-derived teratocarcinoma cell lines. Nature 309,255-256.

4. Evans, M., Bradley, A., and Robertson, E. (1985) EK cell contribution to chi-

meric mice: from tissue culture to sperm, m Genetic Manipulation of the Early Mammalian Embryo, Banbury report 20 (Costantmi, F. and Jaenisch, R., eds.), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 93-102.

5. Beddington, R. S. P. and Robertson, E. J. (1989) An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo. Development 105, 733-737.

6. Suemon, H , Kadodawa, Y., Goto, K., Araki, I, Kondoh, H., and Nakatsuju, N. (1990) A mouse embryonic stem cell line showing plunpotency of differentiation in early embryos and ubiquitous (3-galactosidase expression. Cell Diff Dev. 29,181-186.

7. Nagy, A., Gocza, E., Merentes Diaz, E., Pideaux, V. R., Ivanyi, E., Markulla, M., and Rossant, J. (1990) Embryonic stem cells alone are able to support fetal development m the mouse. Development 110, 815-821.

8 Hardy, K„ Carthew, P., Handyside, A. H., and Hooper, M. L. (1990) Extragonadal teratocarcinoma derived from embryonal stem cells in chimeric mice. J. Pathol. 160, 71-76.

9. Mansour, S. L., Thomas, K. R„ and Capecchi, M. R. (1988) Disruption of the proto-oncogene int-2 m mouse embryo-derived stem cells- a general strategy for targeting mutations to non-selectable genes. Nature 336, 348-352.

10 Capecchi, M. R. (1989) The new mouse genetics: altering the genome by gene targeting. Trends Genet 5,70-76.

11. Schwartzberg, P. L., Goff, S. P., and Robertson, E. J. (1989) Germ-lme transmission of a c-alb mutation produced by targeted gene disruption in ES cells. Science 246, 799-803.

12. Thompson, S., Clarke, A. R„ Pow, A. M., Hooper, M. L., and Melton, D. W. (1989) Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells. Cell 56, 313-321,

13. DeChiara, T. M„ Efstratiadis, A., and Robertson, E. J. (1990) A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345, 78-80.

14. DeChiara, T. M„ Robertson, E, J„ and Efstratiadis, A. (1991) Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64, 849-859.

15. Thomas, K. R. and Capecchi, M. R. (1990) Targeted disruption of the murine int-1 proto-oncogene resulting m severe abnormalities in midbrain and cerebellar development. Nature 346, 847-850.

16. Robertson, E. J. (1991) Using embryonic stem cells to introduce mutations into the mouse germ line. Biol. Reprod. 44,238-245.

17. Bradley, A., Hasty, P., Davis, A., andRamirez-Solis, R. (1992) Modifying the mouse: design and desire. Biotechnology 10,534-539.

18. Whittingham, D. G. (1971) Culture of mouse ova. J. Reprod. Fertil. 14 (Suppl.), 7-21.

19. Fulton, B. P. and Whittingham, D. G. (1978) Activation of mammalian oocytes by intracellular injection of calcium. Nature 273,149-151.

20. Bradley, A. (1987) Production and analysis of chimeric mice, in Teratocarci-nomas and Embryonic Stem Cells: A Practical Approach (Robertson, E. J., ed.), IRL Press, Oxford, pp. 113-151.

21. Lallemand, Y. and Brulet, P. (1990) An in situ assessment of the routes and extents of colonization of the mouse embryo by embryonic stem cells and their descendents. Development 110,1241-1248.

22. Lewis, N. E. and Rossant, J. (1982) Mechanism of size regulation in mouse embryo aggregates. J. Embryol. Exp. Morphol. 72,169-181.

23. Fujii, J. T. and Martin, G. R. (1983) Developmental potential of teratocarcinoma stem cells in utero following aggregation with cleavage-stage mouse embryos. J. Embryol. Exp. Morphol. 74, 79-96.

24. Robertson, E. J. and Bradley, A. (1986) Production of permanent cell lines from early embryos and their use in studying developmental problems, in Experimental Approaches to Mammalian Embryonic Development (Rossant, J. and Pederson, R. A., eds.), Cambridge University Press, Cambridge, pp. 475-508.

25. Wells, D. N„ Wilmut, I., McWhir, J., Campbell, K„ and Hooper, M. L. (1993) in preparation.

26. Stewart, T. A. andMmtz, B. (1981) Successive generations of mice produced from an established culture line of euploid teratocarcinoma cells. Proc. Nat. Acad. Set. USA 78,6314-6318.

27. Stewart, T. A. and Mintz, B. (1982) Recurrent germ-line transmission of the teratocarcinoma genome from the METT-1 culture line to progeny in vivo. J. Exp. Zool. 224,465-469.

28 Robertson, E J., Evans, M. J , and Kaufman, M. H. (1983) X-chromosome instability in pluripotential stem cell lines derived from parthenogenetic embryos. J. Embryol. Exp. Morphol. 74, 297-309.

29. Suda, Y., Suzuki, M., Ikawa, Y., and Aizawa, S. (1987) Mouse embryonic stem cells exhibit indefinite proliferative potential. J. Cell. Physiol. 133,197-201.

30. Robertson, E J. (1986). Pluripotential stem cell lines as a route into the mouse germ line. Trends Genet. 2, 9-13.

31. Stewart, C. L., Vanek, M., and Wagner, E. F. (1985) Expression of foreign genes from retroviral vectors in mouse teratocarcinoma chimeras. EMBO J. 4, 3701-3709.

32. Barbault, H. and Kemler, R. (1989) Embryonic stem cell culture and gene targeting in transgenic mice. Mol. Biol. Med. 6,481-492.

33. Eicher, E. M. and Washburn, L. L. (1978) Assignment of genes to regions of mouse chromosomes. Proc. Nat. Acad. Sci. USA 75,946-950.

34. McLaren, A and Buehr, M. (1981) GPI expression m female germ cells of the mouse. Gen. Res Cambridge 37, 303-309

35. Gossler, A., Joyner, A. L , Rossant, J., and Skarnes, W. C. (1989) Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes. Science 244,463-465.

36. Rossant, J. and Joyner, A. L. (1989) Towards a molecular-genetic analysis of mammalian development. Trends Genet. 5,277-283.

Was this article helpful?

0 0

Post a comment